- Mozart Therapeutics, a Seattle-based biotech startup, raised $55m funding. - The round was led by ARCH Venture Partners along with Sofinnova Partners. - Other backers include MRL Ventures Fund from Merck, Leaps by Bayer, and Eli Lilly & Company.

– Recuro Health is a Dallas, TX-based integrated digital health solutions company.
– Company raised $15m in Series A funding.
– The round was led by ARCH Venture Partners, with participation from OLSF Ventures, Cortado Ventures, 1843 Capital and Sage Venture Partners.
– The new investment will be used to execute the company’s ongoing acquisition and expanded marketing strategy, as well as to further build upon growth since the launch in March 2021.

– Slingshot Biosciences closed a $23m Series A financing.
– The investment was led by Northpond Ventures, with participation from ARCH Venture Partners and Anterra Capital.
– The new funding will enable Slingshot to accelerate the commercialization of its synthetic cell products spanning controls, diagnostics, and adoptive cell therapies.
– Adam Wieschhaus, PhD, Director at Northpond Ventures, and Corey Ritter, Senior Associate at ARCH Venture Partners, will join the Board of Directors.
– Slingshot will also invest heavily in its broader adoptive cell therapy and therapeutics platform with this growth financing.
– Cell-derived products comprise the basis of important healthcare technologies worldwide.

– Prime Medicine is a Cambridge MA-based biotechnology company developing gene editing technology.
– The company raised $115M in Series A funding and $200M in Series B funding.
– The Series A round was led by ARCH Venture Partners with participation from F-Prime Capital, GV, and Newpath Partners.
– The Series B included all Series A investors, plus Casdin Capital with participation from Cormorant Asset Management, Moore Strategic Ventures, Public Sector Pension Investment Board, Redmile Group and Samsara BioCapital.

– ImmuneID, Inc. has raised $50m in Series A financing.
– The round was led by new investor Alta Partners and included new investors Alexandria Venture Investments, Redwood Capital Investments, Section 32 and Tekla Capital Management.
– All existing investors participated in the financing, including Arch Venture Partners, Longwood Fund, Pitango HealthTech, In-Q-Tel, Xfund and others.
– Proceeds from the financing will be used to advance the development of therapeutic candidates to treat autoimmune diseases, severe allergies, cancer and infectious diseases.

– HiberCell, a NYC-based biotechnology company developing therapeutics focused on preventing cancer relapse and metastasis, completed a Series B financing round for gross proceeds of $67.4m.
– The company closed on a $30m debt facility with Hercules Capital, Inc. (NYSE: HTGC).
– The Series B round included new investors Huizenga Capital Management, Monashee Investment Management, funds managed by Tekla Capital Management LLC, Hercules Capital, Mount Sinai Innovation Partners and other undisclosed investors.
– Returning investors, including ARCH Venture Partners, Magnetic Ventures, Bristol Myers Squibb, Trinitas Capital, and others from the Series A syndicate also participated in the round.

– Interline Therapeutics from San Francisco, CA develops a precision medicine platform focused on three essential areas: Genomics, Communities and Modulators.
– The company raised $92M in funding.
– The round was led by Foresite Capital and ARCH Venture Partners.
– The new investment will be used to expand the research platform and advance six preclinical therapeutic programs.

– Ultivue announced the completion of a $50m Series D round of financing.
– New investors include Ally Bridge Group, Pura Vida Investments and Tao Capital Partners.
– Previous venture investors in Ultivue who also participated in the financing include ARCH Ventures, Northpond Ventures and Applied Ventures, LLC.
– This additional funding will help Ultivue strengthen its position in the market, deliver innovative solutions to address the dynamic nature of tumor biology from precious tissue samples and to provide researchers and pathologists with the ability to fully realize the potential of tissue biomarkers within digital pathology workflows.

– Jaguar Gene Therapy announced a $139m Series B funding co-led by Eli Lilly and Company and Deerfield Management.
– Also participating in the round were ARCH Venture Partners, Goldman Sachs, and Nolan Capital.
– The company is advancing AXV101, a gene therapy treatment for BBS1, a subset of Bardet-Biedl syndrome (BBS). A life-threatening neurometabolic condition, BBS causes progressive vision loss, severe obesity, learning disorders and kidney disease.
– The company is leveraging a proven management team with the expertise to accelerate the development, manufacturing and commercialization of novel gene therapy treatments for patients suffering from severe genetic diseases.
– Jaguar is led by former AveXis leadership.

– Vizgen from Cambridge, MA develops genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease with spatial context.
– Series B $37m round was led by Novalis LifeSciences LLC and current investor Northpond Ventures with participation from new investors Tao Capital Partners, Pura Vida Investments, LLC, and a large U.S. endowment fund, and current investors ARCH Venture Partners and David Walt, Ph.D., Professor at Harvard Medical School, Core Faculty at the Wyss Institute, and co-founder of Vizgen.
– The company intends to use the funds to accelerate growth and infrastructure expansion leading up to full commercial launch.

– Insitro, a machine learning-driven drug discovery and development company, has raised $400m in a Series C financing.
– The financing was led by Canada Pension Plan Investment Board (CPP Investments), with significant participation from current investors Andreessen Horowitz, funds and accounts advised by T. Rowe Price Associates, Inc., Casdin Capital, and funds and accounts managed by BlackRock as well as ARCH Venture Partners, Foresite Capital, GV, Third Rock Ventures, Two Sigma Ventures, HOF Capital and Alexandria Venture Investments.

– Seattle’s Presage Biosciences announced $13m in funding.
– The funding was led by Arch Venture Partners and joined by existing investors, including Takeda Pharmaceutical, Celgene and Bristol Myers Squibb (BMS).
– The company has raised a total of $35m in equity.
– Presage is a biotech device company that has built a platform for testing new cancer drugs used to treat tumors.

– eGenesis from Cambridge, Mass. develops human-compatible organs, tissues, and cells.
– The company raised $125m in Series C funding.
– Backers included Farallon Capital Management, Polaris Partners, HBM Healthcare Investments, Invus, Samsara BioCapital, LifeSci Venture Partners, Irving Investors, Catalio Capital Management, SymBiosis, Altium Capital, Monashee Investment Management, and Osage University Partners and existing investors Leaps by Bayer, Fresenius Medical Care Ventures, ARCH Venture Partners, Wellington Partners, Khosla Ventures, and Alta Partners.

– Vividion Therapeutics, Inc., a biotechnology company utilizing novel discovery technologies to unlock high value, traditionally undruggable targets with precision therapeutics for devastating cancers and immune disorders, announced the completion of a $135 million Series C financing.
– The round was co-led by new investors, Logos Capital and Boxer Capital of Tavistock Group.
– Additional new investors in the raise include SoftBank Investment Advisers, Avoro Capital Advisors, funds and accounts managed by BlackRock, RA Capital Management, funds and accounts advised by T. Rowe Price Associates, Inc., Surveyor Capital (a Citadel company), Woodline Partners LP, Acuta Capital and Driehaus Capital Management, alongside existing investors ARCH Venture Partners, BVF Partners L.P., Casdin Capital, Mubadala Capital, Nextech Invest and Versant Ventures.