Topspin Partners

Founded 2000
Founders Leigh J. Randall Leo Guthart Stephen M. Lebowitz


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This summary is composed by our algorithm based on the analysis of the deals. If you think that some of this information is not accurate, please let us know about it and provide any supporting evidences if possible. Such cases will be analyzed by our ML-algorithm and implemented in our database, which will improve this summary.
Total investments 47
Average round size
The average size of a deal this fund participated in
Portfolio companies 26
Rounds per year 2.24
Lead investments 10
Follow on index
How often the fund supports its portfolio startups at next rounds
Exits 12
Key employees 5
Stages of investment
Early Stage Venture
Late Stage Venture

Areas of investment

  • Biotechnology
  • Health Care
  • Pharmaceutical
  • Genetics
  • Medical

The leading representative office of defined VC is situated in the Roslyn Heights. The company was established in North America in United States.

Among the most popular portfolio startups of the fund, we may highlight Alector, NGM Biopharmaceuticals, Celmatix. The fund has no exact preference in a number of founders of portfolio startups. If startup sums 4 of the founder, the chance for it to be financed is low. Moreover, a startup needs to be at the age of 4-5 years to get the investment from the fund. We can highlight the next thriving fund investment areas, such as Health Care, Genetics. For fund there is a match between the country of its foundation and the country of its the most frequent investments - United States.

Considering the real fund results, this VC is 11 percentage points more often commits exit comparing to other organizations. The important activity for fund was in 2015. The common things for fund are deals in the range of 10 - 50 millions dollars. The top amount of exits for fund were in 2019. This Topspin Partners works on 2 percentage points more the average amount of lead investments comparing to the other organizations. The fund is constantly included in 2-6 investment rounds annually.

The usual cause for the fund is to invest in rounds with 4-5 partakers. Despite the Topspin Partners, startups are often financed by OrbiMed, OUP (Osage University Partners), Versant Ventures. The meaningful sponsors for the fund in investment in the same round are OrbiMed, Venrock, Third Rock Ventures. In the next rounds fund is usually obtained by The Column Group, OrbiMed, GV.

The fund was created by Leigh J. Randall, Leo Guthart, Stephen M. Lebowitz. Besides them, we counted 5 critical employees of this fund in our database.

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Notable deals

CompanyIndustryRound SizeDateInvestorsLocation

Coop Home Goods

Consumer Goods
17 Aug 2021 Pico Rivera, California, United States


10 Aug 2021 Waukesha, Wisconsin, United States


28 May 2020 -


$20M13 Jan 2020 New York, United States

PMV Pharmaceuticals

Health Care
Medical Device
$62M13 Nov 2019 Redwood City, California, United States

SetPoint Medical

Health Care
Medical Device
$15M18 Sep 2019 Santa Clarita, California, United States

ORIC Pharmaceuticals

Health Care
$55M09 Aug 2019 South San Francisco, California, United States

Rapt Therapeutics

$37M19 Jun 2019 South San Francisco, California, United States


Health Care
$6M01 Apr 2019 New York, United States


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