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Domain Associates

Investor type Venture Capital


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This summary is composed by our algorithm based on the analysis of the deals. If you think that some of this information is not accurate, please let us know about it and provide any supporting evidences if possible. Such cases will be analyzed by our ML-algorithm and implemented in our database, which will improve this summary.
Total investments 303
Average round size
The average size of a deal this fund participated in
Portfolio companies 153
Rounds per year 8.19
Lead investments 46
Follow on index
How often the fund supports its portfolio startups at next rounds
Exits 85
Key employees 9
Stages of investment
Early Stage Venture
Late Stage Venture
Private Equity

Areas of investment

  • Biotechnology
  • Health Care
  • Medical
  • Pharmaceutical
  • Medical Device

Domain Associates appeared to be the VC, which was created in 1985. The main office of represented VC is situated in the San Diego. The venture was found in North America in United States.

Besides them, we counted 9 critical employees of this fund in our database.

The fund has exact preference in some founders of portfolio startups. When startup sums 5+ of the founder, the probability for it to get the investment is little. Among the most successful fund investment fields, there are Health Diagnostics, Biotechnology. For fund there is a match between the country of its foundation and the country of its the most frequent investments - United States. Among the most popular portfolio startups of the fund, we may highlight Pharmion, Santarus, Tobira Therapeutics. Besides, a startup needs to be aged 4-5 years to get the investment from the fund.

The increased amount of exits for fund were in 2014. The fund is constantly included in 7-12 deals per year. Comparing to the other companies, this Domain Associates performs on 3 percentage points less the average number of lead investments. Deals in the range of 10 - 50 millions dollars are the general things for fund. When the investment is from Domain Associates the average startup value is 50-100 millions dollars. The high activity for fund was in 2012. Despite it in 2019 the fund had an activity. Considering the real fund results, this VC is 1 percentage points more often commits exit comparing to other organizations.

The usual cause for the fund is to invest in rounds with 4-5 partakers. Despite the Domain Associates, startups are often financed by Montreux Equity Partners, Johnson & Johnson Development Corporation, Venrock. The meaningful sponsors for the fund in investment in the same round are Morgenthaler Ventures, Venrock, MPM Capital. In the next rounds fund is usually obtained by Kleiner Perkins, Johnson & Johnson Development Corporation, Canaan Partners.

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Related Funds

Funds investing in previous rounds
These funds often invest in the rounds preceeding the rounds of Domain Associates:
Typical Co-investors
Domain Associates is more likely to invest in rounds together with the following funds:
Funds investing in following rounds
These funds have a tendency to invest in the following rounds after Domain Associates:

Funds with similar focus

Funds from United States
Funds with similar focus located in United States:
Funds with the same geo focus
Funds with similar geography of portfolio companies:
Funds doing lead investments
Funds with similar focus acting as lead investors:

Notable deals

CompanyIndustryRound SizeDateInvestorsLocation

Axial Biotherapeutics

$37M13 Oct 2021 Massachusetts, United States

Antios Therapeutics

$96M12 Apr 2021 Atlanta, Georgia, United States

Fractyl Laboratories

Health Care
Medical Device
$55M06 Aug 2020 Massachusetts, United States

Nobias Therapeutics

Health Care
$3M24 Jul 2020 New Jersey, United States

Exalys Therapeutics

Life Science
$15M16 Jul 2020 San Diego, California, United States

Seraphina Therapeutics

Health Care
$5M18 May 2020 San Diego, California, United States

Aspen Neuroscience

$70M01 Apr 2020 San Diego, California, United States


Life Science
$60M09 Jan 2020 San Diego, California, United States


Health Care
Health Diagnostics
$28M17 Dec 2019 Carlsbad, California, United States
Antios Therapeutics Raises $96M in a Series B

– Antios Therapeutics from San Diego, CA announced the successful completion of a $96m Series B financing.
– The financing was led by Soleus Capital with participation from new major investors RA Capital Management, Adage Capital Management LP, Pontifax and Aisling Capital as well as other healthcare focused funds, Altium Capital, Amzak Health, Granite Point Capital Management, LP, and LifeSci Venture Partners and participation from all of the original Series A investors including Lumira Ventures, CAM Capital, Delos Capital, Domain Associates and Sixty Degree Capital.
– Antios Therapeutics is a clinical-stage biopharmaceutical company focused on the development of innovative therapies to treat and cure viral diseases.


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